Moyamoya syndrome is a rare condition in which blood vessels at the base of the skull progressively narrow, limiting the flow of oxygenated blood to the brain. Surgical treatment options for Moyamoya syndrome include direct revascularization procedures such as an EC-IC bypass as well as indirect revascularization procedures like encephaloduroarteriosynangiosis (EDAS) and pial synangiosis. Here at Columbia University Medical Center/NewYork-Presbyterian Hospital, our neurosurgeons have particular expertise using these and other surgeries to treat patients with Moyamoya syndrome.
“Moyamoya” means “puff of smoke” in Japanese, and the condition is so named because the body grows a secondary network of small vessels in an effort to compensate for the restricted blood flow. On an arteriogram, the network of new vessels resembles a cloud–or puff of smoke. Moyamoya is more common in Japan than in the U.S., but it is unusual everywhere.
The blood vessel network that gives Moyamoya its name may lead to complications. As blood flow becomes increasingly restricted, the supplementary network may become inadequate as an alternative blood supply to the brain. This can lead to cerebral ischemia. In addition, the new vessels are fragile and may rupture.
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