Epilepsy is a truly interdisciplinary specialty. The Columbia Comprehensive Epilepsy Center (CCEC) is a global leader in epilepsy diagnosis and treatment, made up of dedicated specialists in epilepsy neurology, neurophysiology, neuroradiology, neuropsychology, and neurosurgery.
Epilepsy is a truly interdisciplinary specialty. The Columbia Comprehensive Epilepsy Center(CCEC) is a global leader in epilepsy diagnosis and treatment, made up of dedicated specialists in epilepsy neurology, neurophysiology, neuroradiology, neuropsychology, and neurosurgery. The CCEC is equipped with state-of-the-art adult and pediatric epilepsy monitoring units at Columbia University Medical Center and the Morgan Stanley Children’s Hospital.
For forms of epilepsy that cannot be adequately controlled with antiseizure medications, epilepsy surgery is the best and often the only chance of seizure control or cure. A variety of highly specialized techniques are applied to maximize the efficacy and safety of epilepsy surgical procedures.
Members of the Department of Neurosurgery, Dr. Sameer A. Sheth (Adult Epilepsy), Dr. Guy McKhann (Adult and Pediatric Epilepsy), and Dr. Neil Feldstein (Pediatric Epilepsy) comprise one of the most experienced and skilled epilepsy surgery teams in the world. Research consistently finds that experienced surgeons at neuroscience centers of excellence achieve the best possible patient outcomes.
With the CCEC, our epilepsy surgery team is continually engaged in clinical investigations of all of the major epilepsy surgical therapies currently under trial as part of multi-institutional NIH- or industry-sponsored studies, such as responsive brain stimulation (RNS), deep brain stimulation (DBS) (for various forms of focal epilepsy); gamma knife radiosurgery for the treatment of temporal lobe epilepsy, and the investigation of a multichannel microelectrode for microseizure detection.
The Epilepsy Center Team
- Direct, intraoperative observation of ~0.1 Hz hemodynamic oscillations in awake human cortex: implications for fMRI.
- Ictal high frequency oscillations distinguish two types of seizure territories in humans.
- Mechanisms underlying selective neuronal tracking of attended speech at a "cocktail party".
- Exemplar selectivity reflects perceptual similarities in the human fusiform cortex.
- Overcoming barriers to successful epilepsy management.
- The mTOR pathway is activated in glial cells in mesial temporal sclerosis.
- The ERSET trial of early surgery for mesial temporal lobe epilepsy: results and frustrations.
- Epidermoid tumors of the temporal lobe as epileptogenic foci.
- Tuning of the human neocortex to the temporal dynamics of attended events.
- Game-changing, or business as usual? New findings on naming skills after temporal lobe surgery.
- Does cortical mapping protect naming if surgery includes hippocampal resection?
The U.S. Food and Drug Administration (FDA) has just approved the Neuropace RNS Stimulator, an implantable device shown to reduce the frequency of seizures in epilepsy patients. The device is comprised of a small neurostimulator that is implanted in the skull under the skin and two electrodes placed on or near the part of the brain where the patient's seizures arise...